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If You Get Migraines, RDs Recommend Monitoring Your Consumption of Foods (and Drinks) Rich in Tyramine

Parmesan cheese, salami, cornichons, smoked fish…what do all of them have in widespread? In addition to being glorious additions to a cheese and charcuterie board, these scrumptious meals are excessive in tyramine. This lesser-known amino acid spinoff may not ring any alarm bells for you, and for a lot of of us, it would not have to. However you probably have melancholy, nervousness, and/or migrainesβ€”and are on particular drugs to deal with these circumstancesβ€”you may wish to take a better have a look at your tyramine consumption, as a result of it is perhaps making your signs worse.

To find what these potential dietary don’ts areβ€”and what tyramine is to start withβ€”we consulted Dani Lebovitz, MS, RDN, a meals training professional and the founding father of Child Meals Explorers primarily based in Franklin, Tennessee.

What’s tyramine?

β€œTyramine, a pure substance in our our bodies, helps handle blood strain and mind alerts,” Lebovitz explains. Deriving from the amino acid tyrosine, it’s additionally present in widespread meals and drinks. (It is in the identical chemical group because the neurotransmitters dopamine, norepinephrine, and serotonin.)

Whereas tyramine has an necessary job in your physique, issues can get dangerous if you happen to take monoamine oxidase inhibitors (MAOIs), a category of medicines used to deal with melancholy and nervousness. MAOIs assist regulate temper by blocking monoamine oxidase, an enzyme that removes neurotransmitters like serotonin, dopamine, and norepinephrine (stuff you want for steady temper ranges) out of your mind. However MAOIs additionally stop the breakdown of extra tyramine within the physiqueβ€”as a result of keep in mind, tyramine is said to these neurotransmitters.

Except you watched or know for positive that tyramine is a set off for you, there’s no want to chop high-tyramine meals out of your food plan.

Having a surplus of tyramine can result in complications, chest ache, and blurred imaginative and prescient, in addition to blood strain spikes which will require speedy medical consideration. These taking MAOIs might keep away from sure meals1, and similar goes for folks liable to migraines. And whereas tyramine consumption might be included in that, specialists warning in opposition to making dietary adjustments with out consulting a skilled dietitian or doctor. “It is all about how your physique processes tyramine,” she explains. β€œSlicing again on meals excessive in it will probably make an enormous distinction in managing these circumstances.” However there are not any ensures, so converse together with your healthcare supplier about tyramine-rich meals earlier than you forego purple wine or ramen with out motive.

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What meals include tyramine?

Talking of which: A number of meals include tyramine, however fermented or aged meals and drinks are inclined to have probably the most tyramine. That is as a result of microbes convert tyrosine (the amino acid) into tyramine because the meals age2. So the extra “aged” or fermented one thing is, the extra seemingly it’s to have a lot of tyramine.

Meals excessive in tyramine

Lebovitz says that the next meals are usually very excessive in tyramine:

  • Aged cheese (equivalent to Parmesan, Swiss, Stilton, and Gorgonzola)
  • Dry-cured meats (like salami or pepperoni)
  • Pickled meals (like kimchi, sauerkraut, or pickles)
  • Salt-dried seafood
  • Liver
  • Sure beans (like Haricot beans)
  • Fish sauce
  • Soybeans, tofu, and different soybean merchandise
  • Miso

Alcohol can also be excessive in tyramine due to its strategies of manufacturing. β€œAlcoholic drinks like beerβ€”particularly draught and craft beersβ€”together with purple wines are recognized for his or her excessive tyramine ranges,” Lebovitz says.

In the event you’re attempting to keep away from high-tyramine meals and drinks, Lebovitz says you may wish to reduce on espresso as a result of the impact of an excessive amount of caffeine (like complications and a racing heartbeat) can mimic these of tyramine. β€œDue to this fact, people delicate to tyramine may profit from moderating their caffeine consumption,” she says.

β€œAlcoholic drinks like beerβ€”particularly draught and craft beersβ€”together with purple wines are recognized for his or her excessive tyramine ranges,” Lebovitz says.

Low-tyramine meals

In the event you and your healthcare group discover that you may benefit from a low-tyramine food plan, there’s no scarcity of wholesome meals to take pleasure in. Per Lebovitz, they embrace the next:

  • Fruits: Apples, pears, strawberries, blueberries, peaches, plums, and bananas that aren’t overripe
  • Greens: Leafy greens, carrots, tomatoes, potato, zucchini, and turnips
  • Dairy: recent milk, yogurt, and non-fermented cheeses equivalent to cream cheese, cottage cheese, and ricotta
  • Protein: recent meats, fish, poultry, eggs, beans, canned legumes (excluding fava and broad beans)
  • Complete grains: rice, pasta, and bread
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As a basic rule of thumb, Lebovitz says you may reach following a low-tyramine food plan by consuming the meals above in a immediate method and listening to how they’re saved and ready. β€œFor recent produce, devour it inside a few days of buy. For canned or frozen meals, use them quickly after opening, too,” she advises. In the case of recent animal proteins, she suggests consuming or freezing them the identical day of buy.

Ought to everybody restrict tyramine?

No, not everybody must stress about tyramine. Some folks might have to take further care to restrict their consumption of tyramine meals primarily based on their well being circumstances and drugs. Others could also be extra delicate to it than others, and a few folks might course of it simply positive. Except you watched or know for positive that tyramine is a set off for you, there’s no want to chop high-tyramine meals out of your food plan.

It’s at all times greatest to seek the advice of your health-care supplier earlier than making any main adjustments to your food planβ€”particularly if you happen to’re managing medical circumstances. β€œIn the event you suppose you might have a tyramine sensitivity, preserving a meals log could be a useful instrument to determine patterns and potential triggers,” Lebovitz shares. β€œAssembly with a dietitian [who can] provide personalised steering may be useful.”


Nicely+Good articles reference scientific, dependable, latest, sturdy research to again up the data we share. You possibly can belief us alongside your wellness journey.

  1. Van den Eynde, Vincent et al. β€œThe Prescriber’s Information to the MAOI Weight loss program-Considering By way of Tyramine Troubles.” Psychopharmacology bulletin vol. 52,2 (2022): 73-116.
  2. Anderegg, Janine et al. β€œResults of Sodium Chloride on Tyramine Manufacturing in a Fermented Meals Mannequin and its Inhibition by Tyrosine-degrading Lactobacillus plantarum JA-1199.” Chimia vol. 74,5 (2020): 391-397. doi:10.2533/chimia.2020.391
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